Are You Aware of the CBD Oil Role in Our Cellular Function?
September 27, 20225 min read
Are You Aware of the CBD Oil Role in Our Cellular Function?
Many scientific studies suggest that CBD plays many therapeutic roles in the human body. This article discusses the CBD's roles in cellular functions.
The potential effects of CBD and its cellular relation have most to do with its interaction with proteins on the outer membrane of the mitochondria. CBD is now a well-known potential treatment that can regulate inflammation and other numerous therapeutic benefits. Many people are curious about it, questioning its role in cellular function. CBD is an organic chemical compound mainly found in hemp, and it's used for making many medicines due to its non-intoxicating and nonpsychoactive effects. Most drugs meant to treat therapeutic disorders are associated with opioid abuse. Many people now need to avoid dush effects by using natural organic treatments. CBD has been proven to have the potential to serve the role since there are no side effects when using CBD. Take a look into inner work and learn how CBD interacts with cellular function.
CBD Cellular Function with Mitochondria
Rimmerman et al. (2013) discovered that the membranes of the mitochondria cells have endocannabinoid receptors. The study above determined the endocannabinoid system's roles in the human body. The study found a connection between the endocannabinoid system's roles and the mitochondria's cellular mechanism.
The instruction of CBD and mitochondria is a state of balance in the body's operating system. It also improves autophagy and apoptosis, which makes the body operate at optimum conditions. Many forms of CBD, such as CBD oil strains, interact with mitochondria, improving general health, well-being, and internal balance. However, why is the role of CBD in cellular function based mainly on mitochondria?
Defect in the mechanism of mitochondria is related to various health effects related to metabolism, neurodegeneration, and autoimmune complications. For example, you are likely to contract diabetes, Alzheimer's infection, cardiovascular infections, cancer, and other illnesses if your mitochondria fail or have some defects.
The largest percentage of mitochondria are found within human cells. The red blood cell is responsible for producing about ninety percent of the chemical substance that enables other cells to survive. Mitochondria are also responsible for converting nutrients in the blood into cell energy through a process called oxidative phosphorylation. So, if mitochondria suffer any defects that reduce their efficiency, the Body is subjected to a great threat that may affect the whole system. Taking CBD can fix mitochondrion defects and elevate its working efficiency after taking CBD. The mitochondrion is also responsible for regulating other essential body processes such as hemostasis, death, rejuvenation of cells, and oxidative stress.
The interaction between CBD oil and mitochondria in cellular interaction leads to therapeutic benefits. These effects of CBD oil on cellular function with mitochondria allow it to treat a wide range of health conditions, improving the overall state of living.
CBD Oil Cellular Function in Autophagy and Apoptosis
CBD and mitochondria directly influence the control of apoptosis and autophagy in the human body. Apoptosis is a process that regulates and triggers the death of old cells. Autophagy is the process that controls the breaking and rejuvenation of damaged cells. These processes are essential for the normal functioning of the human Body. For example, apoptosis allows cells to eliminate defected tissues from the Body. Autophagy is responsible for killing any cells that have lost efficiency. Suppose these two processes are not available in the system. Harmful cells regenerate in the body and can be a potential treatment for fatal infections like cancer. Therefore, mitochondria are always the main target when designing drugs to treat cancer.
Solinas et al. (2012) linked CBD to apoptosis. García-Morales et al. (2020) stated that CBD was used to treat breast cancer. According to the study above, CBD efficiently fights breast cancer by apoptosis, eliminating many defective cells without harming healthy cells.
Stanley & Hind (2013) discovered that CBD interacts with the VDAC1 substance in the mitochondrion membrane. It is directly linked to apoptosis. The study also showed that CBD inhibits the VDAC1 protein on the cell membrane of mitochondria hence having immune suppressive and anti-cancer benefits.
By interacting with mitochondria, CBD is believed to enhance autophagy and apoptosis through the endocannabinoid system, thus enabling the Body to stay healthy. The endocannabinoid system has three ways of operation when dealing with cellular functions. They are:
Mitochondrial activity is triggered when the Body is in low cell stressing condition, increasing autophagic cello regeneration.
When the Body is in high cell stress condition, the mitochondrial activity is reduced, thus protecting the cells.
When t he cell stress is super high, as in the case of the development of cancerous cells, CBD increases the stress to achieve apoptosis, alleviating the situation.
Since CBD is chemically similar to endocannabinoids produced by the body, they act on the body similarly but efficiently.
The Role of CBD in Oxidation and Free Radicles
Oxidative phosphorylation is a crucial but complicated body process. It is a process where energy for the cells is generated through transporting electrons. During oxidative phosphorylation, hydrogens, peroxide, and oxygen ions are formed and released to all parts of the body. These molecules are free radicles but are highly unstable. When interacting with cells, they damage DNA, proteins, and cell membranes. Antioxidants from the body or external sources neutralize these unstable molecules, thus reducing long-term damage or oxidative stress. CBD is a potential and efficient antioxidant. When you take it, it triggers CB2 receptors, thus stimulating cell protection.
The Bottom Line
The potential effects of CBD and its cellular relation have most to do with its interaction with proteins on the outer membrane of the mitochondria. CBD is now a well-known potential treatment that can regulate inflammation and other numerous therapeutic benefits. Many people are now curious about it, questioning its role in cellular function. After taking CBD, it is believed that it can fix mitochondrion defects and elevate its working efficiency. Apart from providing energy for cell function, the mitochondrion is also responsible for regulating other essential body processes such as hemostasis, death, rejuvenation of cells, and oxidative stress. Note that defect in the mechanism of mitochondria is related to various health effects related to metabolism, neurodegeneration, and autoimmune complications. Do more research to learn more.
García-Morales, L., Castillo, A. M., Tapia Ramírez, J., Zamudio-Meza, H., Domínguez-Robles, M. D. C., & Meza, I. (2020). CBD Reverts The Mesenchymal Invasive Phenotype Of Breast Cancer Cells Induced By The Inflammatory Cytokine IL-1β. International Journal Of Molecular Sciences, 21(7), 2429.
Rimmerman, N., Ben-Hail, D., Porat, Z., Juknat, A., Kozela, E., Daniels, M. P., ... & Vogel, Z. (2013). Direct Modulation Of The Outer Mitochondrial Membrane Channel, Voltage-Dependent Anion Channel 1 (VDAC1) By Cannabidiol: A Novel Mechanism For Cannabinoid-Induced Cell Death. Cell Death & Disease, 4(12), E949-E949.
Solinas, M., Massi, P., Cantelmo, A. R., Cattaneo, M. G., Cammarota, R., Bartolini, D., ... & Parolaro, D. (2012). Cannabidiol Inhibits Angiogenesis By Multiple Mechanisms. British Journal Of Pharmacology, 167(6), 1218-1231.
Stanley, C. P., Hind, W. H., & O'Sullivan, S. E. (2013). Is The Cardiovascular System A Therapeutic Target For Cannabidiol? British Journal Of Clinical Pharmacology, 75(2), 313-322.