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Can CBG Make You Feel High?

September 15, 2022 5 min read

Can CBG Make You Feel High?

Can CBG Make You Feel High?

Cannabigerol is one of the cannabinoids not too different from cannabidiol. They share more similarities. This article will explain more about cannabigerol (CBG) and whether or not it can make you feel high.

CBG is a non-psychoactive compound. It works by activating the endocannabinoid receptors to provide relief. Furthermore, CBG has different health benefits, including treating glaucoma and relieving pain. Additionally, it has anti-inflammatory, antioxidant, and anti-bacterial properties that relieve inflammation and remove harmful bacteria from the body.

Cannabis compounds are the golden specimen in laboratories today since most compounds have proven beneficial to the body. This has changed the societal view of cannabis. In most states, marijuana products are considered illegal. However, most research studies have supported using cannabis compounds such as cannabidiol (CBD), CBG, and tetrahydrocannabinol (THC) to benefit the body since they can offer various therapeutic properties. CBG is among the most common cannabinoids after CBD and THC. However, among the three compounds, CBG is found in lower quantities, thus making it rare and more expensive. CBG cannot make you feel high since it does not have a psychoactive effect.

CBG: What Is It?

Cannabigerol (CBG) is a cannabinoid derived from the cannabis plant. It is non-hallucinogenic and thus cannot alter the user's mental state. Furthermore, CBG amounts tend to be higher in the younger cannabis plant. In the full-grown plant, the quantity reduces since it is not in its acidic form (CBGA). Moreover, the acidic form of CBG is converted to THC and CBD, which is the reason for the scarcity of CBG.

CBG does not cause a high feeling to the user since it is non-psychoactive. On the other hand, THC is a popular marijuana compound known for its hallucinogenic effect; it can alter the mental functioning of the user.

How CBG Works

The human body has the endocannabinoid system, which is believed to have diverse functions—for example, enhancing the immune system's functioning, regulating appetite and body senses, and maintaining internal and external body balance. The endocannabinoid receptors' structure is believed to be the same as the cannabinoids in the cannabis plant. Therefore, CBG, as a cannabinoid, interacts with the receptors to provide relief.

Just like CBD, CBG works by binding with the CB1 and CB2 receptors. The CB1 receptors are found in the brain and the nerves, while the CB2 receptors are found in the immune system and the rest of the body, unlike THC, which acts on the CB1 in the brain, causing the high feeling.

Research shows that all cannabinoids, including THC, CBD, and CBG, work synergically for the well-being of the body by creating an entourage effect. Additionally, CBD and CBG can reduce the psychotropic effects of THC.

Formulations of CBG

CBG is majorly found in oil form. There are different ways of extracting the compounds from the plant, including using chemicals and CO2. CO2 is the best CBG extraction method since it does not expose the compound to harmful substances that contaminate the compounds and reduce their quality. After extraction, CBG is combined with carrier oils such as coconut oil and hemp seed oil. The oils do not affect the potency of the compounds but make their base. CBG oil can be used orally in this form, depending on the purpose.

Most cannabinoids used for pain relief are topical; thus, the compounds can be infused in skin care products for external use but offer internal relief.

Although CBG is scarce and expensive, it is easier to obtain broad-spectrum CBG, which consists of all cannabinoids, terpenes, and flavonoids except THC. However, cannabis farmers are trying to increase the production of CBG by using genetic manipulation and cross-breeding.

Benefits of CBG

Treating Cancer

Cancer has not been declared a pandemic, but it is one of the diseases giving scientists sleepless nights since it is hard to diagnose and cure it accurately. According to Lu et al. (2017), CBG can help cancer patients by preventing the growth and multiplication of colorectal cancer cells. The increased number of cancer cells causes the disease to advance and affect other healthy organs in the body, increasing the risk of patients succumbing to the condition. Research shows that CBG might prevent and treat colon cancer.

Pain Relief

Acute pain or chronic pain can adversely affect your productivity and daily life. Many over-the-counter painkillers and drugs, such as opioids, can be used to ease the pain. According to Überall (2020), cannabinoids (CBG and CBD) can naturally ease muscle, nerve, and joint pains since they have a soothing and relaxing effect on the body and the brain.

Anti-bacterial and Anti-Fungal properties

Many want to use organic compounds with fewer side effects on the body since over-the-counter anti-bacterial and anti-fungal drugs have several side effects, such as migraines, diarrhea, and inflammation. According to Aqawi et al. (2021), CBG can help treat bacterial and fungal infections due to its anti-bacterial and anti-fungal properties.  CBG is also infused in skin care products to treat bacterial or inflammatory skin infections, including psoriasis and acne.


 Internal and external swelling can affect your daily life and productivity since they make you feel uncomfortable. According to Hill et al. (2016), CBG can help reduce inflammation due to its anti-inflammatory properties. For example, CBG can help treat inflammatory bowel disease (IBD), a health condition causing severe swelling in the bowel. The condition has no cure. However, research shows that inflammatory bowel disease patients exhibited significant improvement after using CBG. However, it is advisable to consult your doctor for any medical use of the compound since the compound has no scientific proof.

Treat Glaucoma

According to Cairns al. (2016), the research showed reduced eye pressure and increased outflow of aqueous humor. Aqueous humor is the fluid produced by the eyes essential for providing nutrition to the eyes and maintaining pressure. On the other hand, glaucoma is an eye condition characterized by high pressure in the eyes. It might lead to blindness when severe.

 Similarities Between CBD and CBG

CBG and CBD are inseparable since they are all cannabinoids. They have diverse similarities, including binding to the CB1 and CB2 receptors. Also, they are both non-psychoactive. The only difference is the quantities.


Cannabigerol is a cannabinoid derived from the cannabis plant. It is non-hallucinogenic. Most research has supported using cannabis compounds such as cannabidiol, cannabigerol, and tetrahydrocannabinol to benefit the body since they can offer therapeutic. CBG is among the most common cannabinoids after CBD and THC. It is scarce and expensive, and you can fit the compound from the compound by using the broad-spectrum CBD, which consists of all cannabinoids, terpenes, and flavonoids except THC. Furthermore, CBG has different health benefits, including treating glaucoma, relieving pain, and anti-bacterial and anti-inflammatory properties. CBD and CBG are quite similar since they bind the CB1 and CB2 receptors and are non-psychoactive.


Aqawi, M., Sionov, R. V., Gallily, R., Friedman, M., & Steinberg, D. (2021). Anti-bacterial properties of cannabigerol toward Streptococcus mutans. Frontiers in Microbiology, 12, 656471.

Cairns, E. A., Baldridge, W. H., & Kelly, M. E. (2016). The endocannabinoid system is a therapeutic target in glaucoma. Neural Plasticity, 2016.

Hill, L. A., Bodnar, T. S., Weinberg, J., & Hammond, G. L. (2016). Corticosteroid-binding globulin is a biomarker of inflammation onset and severity in female rats. The Journal of endocrinology, 230(2), 215.

Lu, X. S., Qiao, Y. B., Li, Y., Yang, B., Chen, M. B., & Xing, C. G. (2017). Preclinical study of cinobufagin as a promising anti-colorectal cancer agent. Oncotarget, 8(1), 988.

Überall, M. A. (2020). A review of scientific evidence for THC: CBD oromucosal spray (nabiximols) in chronic pain management. Journal of pain research, 13, 399.