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Cannabidiol Tablets for Pain, Anxiety, and Depression

September 27, 2022 5 min read

Cannabidiol Tablets for Pain, Anxiety, and Depression

Cannabidiol Tablets for Pain, Anxiety, and Depression

Cannabidiol tablets are well known for their therapeutic properties in reducing pain, anxiety, and depression. This article explains how cannabidiol tablets for anxiety and depression, pain management, and how to choose cannabidiol tablets.

Among the two main chemical compounds (cannabinoids) in the cannabis plant are CBD and THC. CBD has no psychotropic effects, unlike THC, which makes individuals feel high. This is the main reason why most people try it. Hemp-derived CBD is distinct from marijuana since it contains less THC. Although marijuana comprises over 0.3% THC, hemp is below the permissible level of 0.3%. The FDA has only allowed Epidiolex, a drug used to treat seizures brought on by two uncommon kinds of epilepsy, permission to use CBD. Cannabidiol, or CBD, is commonly known as the next big thing among fans. Cannabis has healing abilities from insomnia and pain to gastrointestinal problems and inflammation. Individuals turn to CBD to treat mental health disorders, including anxiety and depression, and the purported advantages for physical health.

Cannabidiol Tablets for Anxiety and Depression

According to Soleymanpour et al. (2021), CBD tablets might help reduce anxiety in individuals, and a substantial body of clinical research supports these claims. However, despite some encouraging animal experiments, there is less information available on the efficacy of CBD for depression. Huestis et al. (2019) demonstrated that a single dose of CBD tablet could aid in lessening depressive symptoms for as long as a week. According to Yarar (2021), CBD tablets can aid in the restoration of depressed patients' hippocampus and damaged prefrontal cortex neural circuitry. Also, individuals should remember the complex link between depression and anxiety. Both help reduces discomfort, the inability to sleep well, and mood management. More pain is felt when individuals are extra nervous, and far more anxiety is felt when they are sadder. CBD tablet positively impacts the mechanisms that control pain perception, sleep, and mood, among other things. Individuals require these systems to work well if they want to sleep better, feel better, and have less discomfort. Since the endocannabinoid system is not functioning to its full potential, depression, and anxiety are associated with pain relief, poor mood control, and insufficient sleep. Bryden & Szatmari (2020) showed that the correct CBD tablet dosage might help calm obsessive thoughts brought by anxiety, impairing sleep and provoking frightened nighttime awakenings. (However, taking too much in specific individuals can exacerbate anxiety; take the medication slowly and cautiously)

Depression and disturbed sleep are also connected. Over ninety percent of depressed patients report having trouble falling asleep, interrupting their sleep, or waking up early in the day. Their general capacity to control the disease or their mood might benefit from CBD tablets. Ghallager (2013) stated that CBD could potentially treat nightmares, sleepwalking, and disorders like jaw chewing and parasomnias. Several experimental types of research suggest CBD tablets might help control pain, but additional study is still required, such as high-quality medical research. According to Mücke et al. (2018), individuals have optimistic views toward CBD therapy choices and indicate good results when utilizing the drug for ailments related to pain.

CBD Tablets for Pain Management

Some cannabinoids are exogenous and endogenous. According to Cota et al. (2003), endogenous cannabinoids are fats that the body automatically makes. The famous endogenous cannabinoids are 2-arachidonoylglycerol and anandamide. The cannabis plant makes exogenous cannabinoids since the body cannot produce them. Exogenous cannabinoids include examples like cannabigerol, cannabichromene, THC, and CBD. According to Do et al. (2004), endocannabinoid receptors on cells are occupied by cannabinoids, both exogenous and endogenous. CB1 and CB2 receptors are among them. Different cell behaviors are stimulated by this binding activity, which affects the cellular pathways in pain transmission.

CBD might engage with spinal cord neuronal receptors that block inflammatory responses to pain. The endogenous cannabinoid that lessens pain may work more effectively when combined with CBD. Rein & Wyatt (2020) examined the distress effects of CBD in several individuals who had chronic pain following renal transplantation. Some of the selected respondents said their pain had lessened. The study above found that lower CBD dosages provided the most pain relief while experiencing more incredible pain at increased CBD levels.

How to Choose Cannabidiol Tablets

Only one Cannabidiol medication, Epidiolex, is regulated by the Food and Drug Administration (FDA) to treat uncommon epilepsy. This indicates that the Food and drug administration does not oversee CBD products sold legally. When purchasing CBD, consumers should search for high-quality goods from dependable suppliers and sellers. These businesses have each batch of their products tested for purity by an unbiased, outside lab, demonstrating that the product doesn't somehow include unsafe concentrations of toxins or metal.

Quality

High-quality goods are subjected to lab analysis by laboratories unrelated to the producer. They examine CBD goods for harmful chemicals, microbes, heavy metals, and pesticides. Products that go through lab analysis receive a certificate of analysis. This record details the product's CBD concentration, other cannabinoids, the presence of THC, and the outcomes of safety tests. When purchasing a CBD product for pain relief, an individual also could take the following factors into account:

Strength

There are various strengths of CBD products. Those who have never used CBD products may begin with a low concentration and work their way up until they experience the desired results.

THC Content

Federal law permits the sale of hemp products containing no more than 0.3% THC. Before buying, an individual ought to evaluate the THC content.

Hemp Source

Consumers should consider CBD products from businesses that appropriately source their hemp. Many businesses use hemp cultivated in the United States.

Cost

Certain CBD products have a hefty price tag. Individuals should select a CBD product that will match their wallet and be cost-effective after considering how frequently they will be required to take it.

Unsubstantiated Medical Claims:

One should investigate the pharmaceutical claims being made by CBD producers. The FDA has approved just one CBD prescription medication for medical purposes Trusted Source. The FDA advises consumers to seek medical attention as soon as possible after purchasing CBD products that treat serious ailments like Alzheimer's, diabetes, mental health issues, and cancer.

Conclusion

Although CBD tablets have many medicinal benefits, like reducing pain, anxiety, and depression, some individuals reported some side effects like tiredness, changes in appetite, diarrhea, weight changes, and some liver damage.

References

Bryden, P., & Szatmari, P. (2020). Start Here: A Parent's Guide To Helping Children And Teens Through Mental Health Challenges. Simon & Schuster.

Cota, D., Marsicano, G., Tschöp, M., Grübler, Y., Flachskamm, C., Schubert, M., ... & Pagotto, U. (2003). The Endogenous Cannabinoid System Affects Energy Balance Via Central Orexigenic Drive And Peripheral Lipogenesis. The Journal Of Clinical Investigation, 112(3), 423-431.

Do, Y., Mckallip, R. J., Nagarkatti, M., & Nagarkatti, P. S. (2004). Activation Through Cannabinoid Receptors 1 And 2 On Dendritic Cells Triggers NF-Κb-Dependent Apoptosis: A Novel Role For Endogenous And Exogenous Cannabinoids In Immunoregulation. The Journal Of Immunology, 173(4), 2373-2382.

Huestis, M. A., Solimini, R., Pichini, S., Pacifici, R., Carlier, J., & Busardò, F. P. (2019). Cannabidiol Adverse Effects And Toxicity. Current Neuropharmacology, 17(10), 974-989.

Mücke, M., Phillips, T., Radbruch, L., Petzke, F., & Häuser, W. (2018). Cannabis‐Based Medicines For Chronic Neuropathic Pain In Adults. Cochrane Database Of Systematic Reviews, (3).

Rein, J. L., & Wyatt, C. M. (2018). Marijuana And Cannabinoids In ESRD And Earlier Stages Of CKD. American Journal Of Kidney Diseases, 71(2), 267-274.

Soleymanpour, M., Saderholm, S., & Kavuluru, R. (2021, December). Therapeutic Claims In Cannabidiol (CBD) Marketing Messages On Twitter. In 2021 IEEE International Conference On Bioinformatics And Biomedicine (BIBM) (Pp. 3083-3088). IEEE.

Yarar, E. (2021). Role And Function Of The Endocannabinoid System In Major Depressive Disease. Medical Cannabis And Cannabinoids, 4(1), 1-12.