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How CBD Oil, Topical CBD & Oral CBD Helps with Inflammation

August 30, 2022 5 min read

How CBD Oil, Topical CBD & Oral CBD Helps with Inflammation

How CBD Oil, Topical CBD & Oral CBD Helps with Inflammation

Pain and inflammation may be helped by cannabidiol (CBD). There are oils, edibles, and topical versions of CBD, a cannabinoid extracted from the cannabis plant. CBD is rapidly being used as an alternative therapy for several health concerns, including inflammation, even though studies are still in early phases. Acute and chronic inflammation in addition to how CBD works to ease inflammation will be discussed here.

CBD has shown potential in the battle against age-related health concerns for those with both short-term and long-term inflammation. Inflammation and discomfort in the joints are included in this category. Some people choose to use topical CBD, such as massage oils or lotions, and others prefer consumables, such as gummies, to take CBD. People should experiment with various dosages and formats to discover what works best. One will examine CBD and inflammation in this article and some possible therapies. Inflammation is the body's frontline in the event of an injury or illness. When the body identifies a problem, it will send white blood cells to the region. This shields your body from the outer world. Acute and chronic inflammation are the main types of inflammation.

Acute Inflammatory Response

According to Rabb et al. (2016), acute inflammation is far more prevalent. Daily, many individuals undoubtedly feel it without even realizing it. It may happen if you injure your thumb or sprain your ankle. Your body's systems recognize the unexpected damage. Following that, blood flow to the injured site instantly rises. This results in a well-known heated sensation and redness. Then, your body will deploy white blood cells to swoop in and aid in mending. Fluid leakage into muscle tissue is possible due to the substances produced by white blood cells during an attack. Swelling of the affected area is the outcome. Consequently, we feel increased pain at the location of the injury as a result of the whole process. Happily, acute inflammation is, as its names indicate, is brief. The swelling, pain, and redness will begin to fade within the next several hours or days. The amount of time depends on the severity of the damage.

Chronic Inflammation

According to Barnes (2011), chronic inflammation might be far more difficult to deal with. When the body's inflammatory reaction lasts longer than it should, it results in this condition. In some cases, the discomfort persists even after the original inflammation has been effectively managed. The inflammatory process is the same as it is in the acute phase. White blood cells are still being used to fight a disease that no longer exists.

Inflammatory Arthritis 

When your body mistakes good tissue for hazardous microorganisms, it will assault and produce inflammation in joints and the surrounding area regularly. Intermittent joint inflammation is characterized by inflammatory arthritis. According to van der Ven et al. (2017), the fundamental cause of inflammatory arthritis (IA) is difficult to identify. Symptom control is an important part of IA therapy. Pain and swelling flare-ups need additional attention when treating the symptoms that cause them. For most people, this involves taking a mix of anti-inflammatory and pain-relieving drugs. Inflammation is kept in check, and the immunological system is stabilized. When symptoms are absent, it is critical to keep the joints moving to avoid stiffness. Chronic arthritic pain might make it difficult to get out of bed and exercise. One may treat inflammation with a wide variety of medications. Many of these drugs have undesirable long-term adverse effects in exchange for short-term relief from symptoms.

How CBD Works To Ease Inflammation

Phytocannabinoids are unique chemicals found in cannabis plants. The endocannabinoid system, triggered by phytocannabinoids, is found in all mammals. The ECS controls a wide range of bodily functions. These include hunger, pain feeling, mood, and memory.

The Inflammation and Pain Receptors May Be Affected by CBD's Action

CBD has a profound effect on the human body's physiology. The vast majority of these interactions take place at the level of the brain's receptors. As the name suggests, a receptor is simply a protein that attaches to a certain chemical. CBD is the chemical in question here. Two types of brain receptors primarily influence pain and inflammation in the body. The GPR55 and TRPV1 receptors are involved. TRPV1 receptors seem to be the CBD's strongest ally. There are two main ways in which CBD does its work: by attaching to and activating certain receptors. Analgesic (pain-reducing) properties of TRPV1 receptor activation have been shown. According to Devinsky et al. (2014), this receptor is GPR55, a prevalent one in the brain, and it has a crucial role in the interaction between CBD and this receptor. This receptor assists in the disintegration of our bones when it is activated. When this receptor is hyperactive, osteoporosis might occur. For better bone health and even the prevention of the spread of cancer cells, CBD acts as a GPR55 antagonist by blocking the receptor's function.

What Is the Best Way to Consume Cannabidiol (CBD)

A variety of products on the market offer CBD in various ways. The way CBD enters the body has an impact on how much and how quickly it is absorbed and how active it is. A transdermal patch laced with CBD absorbs the circulation significantly more quickly than an oral dose. Various routes of CBD administration are more effective than others in relieving pain and inflammation. Although applying a lotion or salve directly to the affected region may seem logical, topicals do not reach the bloodstream. The use of topical analgesics may be helpful in the treatment of superficial discomfort. CBD, on the other hand, does not enter the circulation to interact with the receptors essential for its effects.


Evidence suggests that CBD decreases inflammation and pain in animals, despite the lack of human investigations exploring the effects of the compound on this physiologic response. Anecdotal evidence shows it may have a similar impact on people. Researchers need to do additional human trials to completely understand how CBD works and how it helps alleviate symptoms like pain and inflammation. With that stated, a variety of CBD products are available, many of which have little or no negative effects.


Barnes, P. J. (2011). Glucocorticosteroids: current and future directions. British journal of pharmacology, 163(1), 29-43.

Devinsky, O., Cilio, M. R., Cross, H., Fernandez‐Ruiz, J., French, J., Hill, C., ... & Friedman, D. (2014). Cannabidiol: pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders. Epilepsia, 55(6), 791-802.

Rabb, H., Griffin, M. D., McKay, D. B., Swaminathan, S., Pickkers, P., Rosner, M. H., ... & Ronco, C. (2016). Inflammation in AKI: current understanding, key questions, and knowledge gaps. Journal of the American Society of Nephrology, 27(2), 371-379.

van der Ven, M., Van Der Veer-Meerkerk, M., Ten Cate, D. F., Rasappu, N., Kok, M. R., Csakvari, D., ... & Luime, J. J. (2017). Absence of ultrasound inflammation in patients presenting with arthralgia rules out the development of arthritis. Arthritis research & therapy, 19(1), 1-7.