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  • August 20, 2022 5 min read


    Applying CBD serum first can increase the skin's ability to absorb active substances. In the majority of skincare regimens, moisturizer is the final step.

    CBD is a chemical component found in Cannabis Sativa. To generate CBD oil, manufacturers can blend CBD with an oil, such as hemp or coconut oil. People can apply CBD oil or a variety of beauty products including CBD oil to their skin. Other CBD products include salve, balm, moisturizer, serum, and cream formulations. But how do they function? In most circumstances, serum should be applied before moisturizer. This is because the serum is typically more lightweight than a moisturizer. Discussed below is a guide on how to use serums and moisturizers.

    Why Is CBD Utilized In Cosmetics?

    The incorporation of CBD oil into beauty products enables regular use of its potential benefits. Cream (2020) stated that the effects of CBD on the skin indicate that combining CBD with hemp oil helps hydrate and repair the skin. However, additional research is required to determine the long-term implications of everyday CBD consumption as it is seen to aid in the reduction of sebocytes. These are the cells that produce sebum, which can lead to acne. This suggests that it may be an effective acne treatment. Baswan et al. (2020) explained that cannabis may also have antibacterial and antifungal properties, which may be beneficial for some skin diseases. However, the majority of claims regarding the effects and advantages of CBD in cosmetic products are anecdotal and unsupported by scientific studies.

    Should Serum Go First

    Typically, it is preferable to apply CBD serum before to moisturizer. Multiple factors support this conclusion. The first is that the majority of CBD serums are water-based fluids or gels with a thin consistency. This means they do not contain any oil and are lightweight. In contrast, the majority of CBD moisturizers contain oil and are typically thicker than serums. Since oil repels water, applying an oil-based moisturizer before a water-based serum could prevent the skin from absorbing the CBD serum's active components. Serums have typically smaller molecular structures than moisturizers, which is a further reason why they are more effective. This enables the delivery of active substances deeper into the skin. A serum could have the following objectives:

    • Minimize the outward manifestations of aging
    • Decrease sun damage
    • A remedy for acne or clogged pores
    • Reduce inflammation or redness
    • Moisten parched, flaking skin
    • To lessen hyperpigmentation

    Before applying other products, applying serum first allows the active components to have the most contact with the skin.

    Application Sequence for CBD Skincare Products.

    It can be challenging to choose when to apply various skincare products for best efficacy. Fortunately, the correct order is typically the same independent of a person's skin type or the cosmetics they employ. For example, a basic morning routine might consist of:

    • A delicate cleaner
    • moisturizer
    • sunscreen

    Evening routines may consist of cleansing or removing makeup, followed by moisturizing. Some individuals use facial oils. These can be substituted for moisturizers because they also lock in moisture. Because they can create a dazzling appearance, face oils may be better utilized at night. After cleansing and before moisturizing, individuals who wish to add a serum to their routine might apply it. Depending on the product, this may occur in the morning or evening. The optimal serum relies on a person's skincare objectives. Before making a decision, it is essential to investigate a product's active ingredients.

    Morning Or Evening

    GUT (2019) explained that certain CBD serums and moisturizers contain chemicals that are best utilized in the morning or evening. These include items that contain: Vitamin C since many individuals use this product to brighten their complexion, morning use may be preferable. These compounds increase the skin's sensitivity to sunlight and can cause inflammation. Therefore, it is ideal to apply retinoid treatments before night. If the product is a serum, applying a calming moisturizer afterward may prevent or alleviate any adverse effects. These products can also increase the skin's sensitivity to light; thus, they are best applied before night. This may also indicate that the product stays on the skin longer.

    CBD Serum And Moisturizer; Ingredients That Should Not Be Mixed

    Certain skincare compounds may irritate the skin when combined, especially with CBD. The following combinations should be avoided:

    Exfoliants and retinoids

    Retinoids are potent medications that can have negative side effects. Downey (2022) explained that combining acid exfoliants with CBD may be too much for certain people's skin. Furthermore, because both drugs increase UV sensitivity, combining the two may render the skin extremely vulnerable to injury. Instead of using both products on the same day, alternate them for extended periods.

    Benzoyl peroxide and retinoids

    The combination of retinoids and benzoyl peroxide may result in severe dryness and irritation. Some claim that retinoids deactivate benzoyl peroxide, but this is yet to be proved. The researchers blended 0.05 percent tretinoin gel with a 5% benzoyl peroxide formulation. After seven hours, 100 percent of tretinoin remained active.

    Potential Dangers

    There has been minimal scientific research into the dangers of utilizing CBD in beauty products.  Cosmetic CBD products are not guaranteed to be safe or effective by the Food and Drug Administration (FDA). Anyone interested in using CBD beauty products should carefully consider any claims made by the makers. If a person begins using CBD skincare products and develops a rash, irritation, or swelling, they should discontinue use and seek medical attention. A selection of products for the lips, face, skin, and hair is provided here. It is vital to highlight that the following comments are solely based on research. These goods have not been tried by anyone at Medical News Today, including the writer.


    It's recommended to use a CBD serum first, then a moisturizer. The serum's active ingredients have the best chance of working if they are applied in this way. Skincare regimens should be performed according to a person's schedule and goals, not the substances in the products themselves. Based on a person's concerns and needs, dermatologists might recommend the best course of action to take. You should also see a dermatologist if you have recurrent skin concerns including dryness, scars, or hyperpigmentation.


    Baswan, S. M., Klosner, A. E., Glynn, K., Rajgopal, A., Malik, K., Yim, S., & Stern, N. (2020). Therapeutic potential of cannabidiol (CBD) for skin health and disorders. Clinical, cosmetic and investigational dermatology13, 927.

    Cream, C. L. F. (2020). Where Nature & Science Meet Skincare, Haircare, Beauty & Wellness. Aging22.

    Downey, M. (2022). Triggering Skin-Cell Renewal. Life.

    GUT, M. (2019). aesthetics.